About 2 results found for searched term "Ruthenium red" (0.179 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10367 | Ruthenium red | Calcium Channel |
| Ammoniated ruthenium oxychloride | ||
| Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red is also a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels. | ||
| M29074 | BOLD-100 | DNA/RNA Synthesis |
| NKP-1339; IT-139; KP-1339 | ||
| BOLD-100 (NKP-1339; IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. BOLD-100 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu. | ||
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